KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
6.06
Human Site:
S405
Identified Species:
10.26
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S405
V
S
T
Q
S
N
G
S
Q
Q
A
W
G
M
R
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S405
V
S
T
Q
S
N
G
S
Q
Q
A
W
G
M
R
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
H395
K
P
E
E
L
S
V
H
N
N
V
L
T
Q
S
Dog
Lupus familis
XP_532028
914
101864
Y487
T
N
P
E
V
H
N
Y
Q
P
Q
Y
H
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
Q405
S
A
Q
K
S
D
S
Q
Q
A
W
G
V
M
S
Rat
Rattus norvegicus
Q5FVG2
731
81700
Q405
S
A
Q
N
N
D
S
Q
Q
A
W
G
M
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
V405
V
P
G
M
A
V
G
V
E
E
A
S
V
G
K
Chicken
Gallus gallus
XP_422083
502
57358
H179
G
D
Y
D
P
A
E
H
V
P
E
L
V
S
E
Frog
Xenopus laevis
NP_001080234
498
57093
D175
Q
G
E
L
G
D
Y
D
P
A
E
H
T
P
D
Zebra Danio
Brachydanio rerio
O57457
619
70690
R296
V
E
H
H
T
F
F
R
M
P
E
N
E
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
A420
V
A
S
V
N
A
R
A
A
A
A
A
A
A
A
Honey Bee
Apis mellifera
XP_623974
809
90976
E485
P
V
I
T
N
E
E
E
S
L
Q
R
Q
S
S
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
N566
A
R
G
L
P
P
T
N
Q
Q
A
Y
N
T
S
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
A400
T
L
P
S
P
G
G
A
S
A
T
S
P
H
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
0
6.6
N.A.
20
6.6
N.A.
20
0
0
6.6
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
100
13.3
33.3
N.A.
40
26.6
N.A.
46.6
0
6.6
13.3
N.A.
40
6.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
0
0
8
15
0
15
8
36
36
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
22
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
8
15
15
0
8
15
8
8
8
22
0
8
0
8
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
15
0
8
8
29
0
0
0
0
15
15
8
0
% G
% His:
0
0
8
8
0
8
0
15
0
0
0
8
8
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
8
0
15
8
0
0
0
0
8
0
15
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
8
22
0
% M
% Asn:
0
8
0
8
22
15
8
8
8
8
0
8
8
0
15
% N
% Pro:
8
15
15
0
22
8
0
0
8
22
0
0
8
15
0
% P
% Gln:
8
0
15
15
0
0
0
15
43
22
15
0
8
8
8
% Q
% Arg:
0
8
0
0
0
0
8
8
0
0
0
8
0
0
15
% R
% Ser:
15
15
8
8
22
8
15
15
15
0
0
15
0
22
36
% S
% Thr:
15
0
15
8
8
0
8
0
0
0
8
0
15
8
0
% T
% Val:
36
8
0
8
8
8
8
8
8
0
8
0
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
15
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
8
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _